Cardiorespiratory coupling is associated with exercise capacity in patients with chronic obstructive pulmonary disease
نویسندگان
چکیده
Abstract Background The interaction between the pulmonary function and cardiovascular mechanics is a crucial issue, particularly when treating patients with chronic obstructive disease (COPD). Synchrogram index new parameter that can quantify this has potential to apply in COPD patients. Our objective study was characterize cardiorespiratory interactions terms of coupling (CRC) using synchrogram heart rate respiratory flow signals disease. Methods This cross-sectional preliminary data from prospective study, which examines 55 K-means clustering analysis applied cluster based on index. Linear regression multivariable were used determine correlation exercise capacity assessed by six-minute walking test (6MWT). Results separated into synchronized group (median 0.89 (0.64–0.97), n = 43) desynchronized 0.23 (0.02–0.51), 12) analysis. correlated significantly six minutes distance (r 0.42, p 0.001) saturation product 0.41, 6MWT, still an independent variable Conclusion first result studying heart–lung index, are clustered groups. Cardiorespiratory associated COPD.
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ژورنال
عنوان ژورنال: BMC Pulmonary Medicine
سال: 2021
ISSN: ['1471-2466']
DOI: https://doi.org/10.1186/s12890-021-01400-1